The Plasma Clearance and Urinary Excretion of Parenterally Administered 58Co B12
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چکیده
منابع مشابه
The plasma clearance and urinary excretion of parenterally administered 58Co B12.
LTERATIONS in the vitansin B12 concentrations of senuns amid umnimsc after the oral or pareisteral adnsitsistratiots of B12 can be followed by mssicrohiological niethods.’7 The imitroduct-iois of radioactive vitamssits B12 labeled with #{176}Co has also nsade it possible to study body distribution of the vitamssims after oral or paremsteral administration to amiinsabs amid humamus.8’3 Changes i...
متن کاملThe urinary excretion of assayable vitamin B12 and radioactivity after parenteral 58Co B12 in man.
Evidence is presented that after injection of radioactive vitamin B(12) in man, there is a close correlation between the amount of radioactivity excreted and the amount of assayable vitamin B(12) excreted, and thus that the amount of radioactivity excreted is a true measure of the vitamin B(12) excreted. The possible reasons for this occurrence are discussed and it is suggested that in the body...
متن کاملUrinary excretion of vitamin B12.
rfHE ANNOUNCE\-IENT of the discoveryof vitamin 1312 in 1948 byRickes, et a!.’ in this coumitry amid hi y Smith, et al.2 in Emiglamid imiitiat-e(! its use in various climiical entities. The principal use has been in the treatment of permiicious -anemia. The dosage of this drug has beemi more or less empirically established!. The hematologic amid subjective responses of the patient with permiicio...
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The present study was conducted on five healthy male cross bred calves to study the kinetic dispositionand urinary excretion of levofloxacin following its single subcutaneous administration at the dose of4 mg.kg-1. The concentration of levofloxacin in plasma and urine samples was estimated by microbiologicalassay. Peak plasma level of levofloxacin (2.8 ± 0.3 μg.ml-1) was observed at 45 min and ...
متن کاملSurface scintillation measurements in humans of the uptake of parenterally administered radioactive vitamin B12.
IN EARLIER WORK'. 2 the metabolism of vitamin B12 was studied in pa-tietits with pernicious and other nutritional anemias. The microbiological assay with E. coli mutant' and Euglena gracilis2 was used for the quantitation of vitamin B12 in urine and blood, following injection or oral administration of vita-mm B12 alone or with various gastric materials of humaii or animal origin, coi'-taming in...
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ژورنال
عنوان ژورنال: Blood
سال: 1956
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v11.1.31.31